Sunday 26 March 2017

Top 10 scariest Diseases of All time.

               Top 10 Scariest diseases

1.    Progeria.
                                                           
                                               

Progeria is an extremely rare genetic disorder in which symptoms resembling aspects of aging are manifested at a very early age. Those born with progeria typically live to their mid teens to early twenties. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson–Gilford progeria syndrome. The word progeria comes from the Greek words "pro" meaning "before" or "premature" and "gēras, meaning "old age". Scientists are partly interested in progeria as it might reveal clues about the normal process of aging.

2  Water allergy.
                                                             
                                             
You people heard many types of allergy but this disorder present with painful rashes that break out wherever water touches the skin. Usually within an hour after contact with water, the sufferer will end up with small wheals, which are raised, reddened areas also known as papules. It’s an extremely rare disorder, with only 100 reported cases worldwide. The diseases cant transfer from one person to another that’s why doctors believed genetics components is involved. However, most cases take place in separate families, with only a few happening to relatives. While some cases can be quite gentle, most are extremely painful, with sufferers resorting to either extremely short baths or none at all in order to avoid the pain.

     3.    Elephantiasis.                           

Elephantiasis is a condition characterized by gross enlargement of an area of the body, especially the limbs. Other areas commonly affected include the external genitals. Elephantiasis is caused by obstruction of the lymphatic system, which results in the accumulation of a fluid called lymph in the affected areas. Functioning as part of the immune system, the lymphatic system helps to protect the body against infection and disease. It consists of a network of tubular channels (lymph vessels) that drain a thin watery as lymph from different areas of the body into the bloodstream. Obstruction of these vessels results in the massive swelling and gross enlargement characteristic of elephantiasis.
4. Clarkson’s desease. 
                                            
                                                                               
It is due pores in the small blood vessels called capillaries due to which fluid leakout into body spaces Although rare, the only way to treat Clarkson's disease is to to inject fluids into the body to counter the bloating. This is a problem in itself since it takes three full days for the bloating to stop - and in the mean time it can lead to damage to vital organs and tissues ultimately causing death.

5.Were wolf syndrome.
                                              

This disease is also know as Hypertrichosis. It is the overproduction of hair anywhere on the body. Men and women, babies and adults -- the condition doesn't discriminate. There are variations of the disorder, some resulting in hair growth patterns that likely contributed to ancient "wolfman" folklore. When present at birth, it's the result of the fine, soft hair that covers a fetus continuing to grow, instead of shedding before birth as it normally does. But more often, it develops as a result of some genetics variation. There is no effective cure for this diseases.
6. FIBRODYSPLASICA OSSIFICANS PROGRESSIVA.
                                            


This disease which is due to some genetics changes With fewer than 800 cases worldwide the disease which is nearly impossible to treat. FOP causes the body's tissue repair systems to stop working and it begins to heal damaged muscles, tendons and tissues by turning them into bone. The new bones do not have flexible joints so once they start to grow throughout the body it becomes nearly impossible for someone with FOP to move. Cutting off the newly formed bones makes the problem even worse as this causes the bone growth to run even more amok. Any knock to the body causes more bones to being growing, thus causing a faster deterioration of the body. In the most extreme instance, a man named Harry Eastlake managed to live up to age 40 with FOP but by the end was completely immobile aside from his lips. Mr Eastlake donated his body to science soon before his death and his skeleton remains at the famous Mutter Museum in Philadelphia, Pennsylvania. 
7. Necrotizing Fasciitis – Flesh eating bacteria.
                                                    

Despite not being the biggest killer out there Necrotizing Fasciitis is just scary. In this disease the bacteria start eating flesh after some trauma if the wound get infected by group A streptococcus  and the skin might start to change color, and blisters form around the outside of the cut, while inside your tissues are slowly dying as toxins are released by this, now, thriving bacterial colony. Eventually this colony will grow up your arm and reach your torso where, if you haven’t  received medical help, you have a 30% chance of surviving. The worst thing about Necrotizing Fasciitis is its ability to spread extremely fast, so fast in fact that even if you do receive medical attention in time, your chances of survival are still extremely low. And if you do survive the infection you will more likely than not be permanently scarred for the rest of your life.
8. Neurofibromatosis.
                            

Neurofibromatosis (NF) is a group of three conditions in which tumors grow in the nervous system. Small lumps arise all over the skin and distort shape of the patient and cause severe disability for the patient .genetics plays important role in this disease and prognosis depend upon the stage in which patient present.
9. Leprosy.
                                                 

Leprosy is a contagious infection that causes inflammation in the skin, eyes, nerves and respiratory tract. It is contracted from exposure to a certain type of bacteria called Mycobacterium. This disease has been discussed in my religious scriptures. Symptoms can actually go unnoticed for years resulting in poor eyesight the loss of feeling in the limbs or infected area. As people lose feeling in their limbs, wounds and infections occur and eventually they may lose parts of their body. Leprosy has been around for thousands of years and in the old days they used to quarantine anyone with leprosy into leper colonies so the disease would not spread. Nowadays due to effective treatment it is very rare to find this disease.

1o. Tree Man syndrome.
                                                     

Epidermodysplasia verruciformis (EV), also known as tree man illness, is an extremely rare hereditary skin disorder associated with a high risk of skin cancer. It is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin and resulting massive number of warts which look like twig coming out of tree. No curative treatment is found yet.
By Dr Aamir Iqbal     









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